Sodium Lauroyl Lactylate

Catalog NumberHG13557750

CAS Number13557-75-0

CategoryAnionic Surfactants

Synonyms

Dodecanoic acid, 2-(1-carboxyethoxy)-1-methyl-2-oxoethyl ester, sodium salt

Molecular Weight

366.42

Molecular Formula

C18H31NaO6

Appearance

Solid

Application

Use as cleansing agent.; Use as dispersing agent, emulsifying agent.; Use as lubricant.

Active Content

85%

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Case Study

Sodium Lauroyl Lactylate as a Membrane-Disruptive Surfactant for Antimicrobial Applications

Gooran, Negin, et al. International Journal of Molecular Sciences 24.11 (2023): 9283.

Sodium lauroyl lactylate (SLL) acts as a membrane-disruptive surfactant with intermediate potency between sodium dodecyl sulfate (SDS) and lauric acid (LA).
Experimental Protocol: The critical micelle concentration (CMC) is determined by wavelength-shift fluorescence spectroscopy using 1-pyrenecarboxaldehyde as a probe. Quartz crystal microbalance-dissipation (QCM-D) measurements track interactions with supported lipid bilayers (SLB) of DOPC at SLL concentrations of 250-2000 M in PBS at pH 7.4. Electrochemical impedance spectroscopy (EIS) is performed on tethered bilayer lipid membranes (tBLM) to evaluate conductance and capacitance changes.
Performance Evaluation: The CMC of SLL is 700 M. At 2000 M, SLL causes complete SLB solubilization (100%) after buffer washing, inducing membrane morphological changes with a maximum dissipation shift of 9 10^-6. EIS data show that SLL causes modest, reversible membrane permeability changes with Gm shifts of 36 8 S. SLL demonstrates intermediate membrane-disruptive activity between the strong solubilization by SDS and the partial disruption by LA.

• Synonyms: Dodecanoic acid, 2-(1-carboxyethoxy)-1-methyl-2-oxoethyl ester, sodium salt
• Molecular Weight: 366.42
• Molecular Formula: C18H31NaO6
• Appearance: Solid
• Application: Use as cleansing agent.; Use as dispersing agent, emulsifying agent.; Use as lubricant.
• Active Content: 85%