Sodium Dodecylpoly(oxyethylene) Sulfate

Catalog NumberHG9004824

CAS Number9004-82-4

CategoryAnionic Surfactants

Synonyms

Sodium Laureth Sulfate

Application

Use as cleansing agent.; Use as emulsifying agent, dispersing agent.; Use as foam stabilizing agent, foaming agent.; Use as solubilizing agent.

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Case Study

Micellization and Tunable Foam Properties in Sodium Laureth Sulfate and Polysorbate Mixtures

Blagojević, Slavica M., et al. Russian Journal of Physical Chemistry A 93.13 (2019): 2804-2811.

This study examined the micellization behavior and foam performance of anionic surfactant sodium laureth sulfate (SLES) when blended with nonionic polysorbate surfactants (Tween series). The study focused on how polysorbate structure and concentration influence critical micelle concentration (CMC) and foam characteristics in SLES-based mixtures.
Methodology: The critical micellar concentration (CMC) of SLES-polysorbate mixtures was determined via specific conductivity measurements at 25°C. Foam height and stability were evaluated using a modified Ross-Miles method at 23°C. The hydrophobic tail length and mole fraction of polysorbates were varied to assess their impact on mixed micelle formation and foam properties.
Key Findings:
· Mixed micelles formed in all SLES-Tween blends, exhibiting non-ideal mixing behavior with clear synergistic interactions.
· Experimentally determined CMC values were lower than theoretical predictions, confirming enhanced micelle stability due to attractive forces between SLES and polysorbates.
· Increasing the polysorbate hydrophobic tail length and mole fraction further reduced CMC, promoting micelle formation at lower concentrations.
· Foam height and stability decreased significantly with longer polysorbate hydrophobic chains and higher polysorbate mole fractions.
· At lower surfactant concentrations, mixed micelles contained a higher proportion of the more hydrophobic polysorbate.

Antimicrobial Efficacy of Sodium Laureth Sulfate in Combination with Plasma-Activated Water

Liu, Xiao, et al. Applied Microbiology and Biotechnology 105.7 (2021): 2855-2865.

This study explored the combined antimicrobial effects of sodium laureth sulfate (SLES) and plasma-activated water (PAW) against Saccharomyces cerevisiae.
Methodology: The antifungal efficacy of the SLES-PAW combination was assessed using both liquid suspension and surface contamination models with S. cerevisiae. Viable cell counts were recorded pre- and post-treatment. To understand the mechanism of action, the analysis included membrane integrity, lipid oxidation, intracellular reactive oxygen species (ROS) levels, and mitochondrial membrane potential (△ψm).
Key Findings:
· SLES at a concentration of 0.50 mg/mL, in conjunction with PAW, quickly inactivated S. cerevisiae, lowering its count from 6.95 log10 CFU/mL to undetectable levels in just 20 minutes.
· On polyethylene surfaces, a SLES concentration of 2.5 mg/mL with PAW resulted in complete inactivation (from 5.84 log10 CFU/cm2 to undetectable) after 30 minutes.
· Treatment with as little as 0.01 mg/mL SLES alongside PAW for 5 minutes significantly disrupted mitochondrial membrane potential (△ψm).
· The combination led to severe membrane damage, increased lipid peroxidation, and heightened intracellular ROS levels.

• Synonyms: Sodium Laureth Sulfate
• Application: Use as cleansing agent.; Use as emulsifying agent, dispersing agent.; Use as foam stabilizing agent, foaming agent.; Use as solubilizing agent.