Dicaprylyl ether

Catalog NumberHG629823

CAS Number629-82-3

CategoryNon-ionic Surfactants

Synonyms

Dioctyl ether

Molecular Weight

242.44

Molecular Formula

C16H34O

Appearance

Liquid

Application

Use as lubricant.; Use as dispersing agent.

Active Content

95%

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Case Study

Development of Stable Gelled Nanoparticle Dispersions Based on Dicaprylyl Ether

Kirilov, Plamen, et al. Colloids and Surfaces A: Physicochemical and Engineering Aspects 328.1-3 (2008): 1-7.

This study outlined the development and characterization of a novel colloidal dispersion system utilizing gelled nanoparticles of dicaprylyl ether. The objective was to produce stable aqueous dispersions of gelled oil nanoparticles using 12-hydroxystearic acid (HSA) as a gelator and either CTAB or PVA80 as stabilizers.
Gel Formation: HSA was dissolved at concentrations ranging from 1% to 15% (by weight of the oil phase) in dicaprylyl ether. The mixture was homogenized using ultrasonic treatment at 75°C for 5 minutes and subsequently cooled to room temperature to form a translucent and structurally stable gel.
Dispersion Preparation: The pre-formed organogel was combined with an aqueous solution containing a stabilizer (CTAB or PVA80). The mixture was heated to 75°C-above the gelation temperature-for 20 minutes until complete melting occurred, resulting in a distinct oil layer. Hot emulsification was then performed via sonication (20 kHz, 600W) at 75°C for two 5-minute intervals. The resulting emulsion was cooled to room temperature to form a dispersion of gelled nanoparticles.
Key Results: Transmission electron microscopy (TEM) revealed spherical nanoparticles with an average diameter of 260 nm, consistent with dynamic light scattering (DLS) measurements. Particle size and dispersion stability were influenced by the concentrations of oil and stabilizer. Rheological analysis confirmed the gelled nature of the particles and the successful adsorption of stabilizers onto their surfaces. A comparative evaluation between the initial emulsion and the final gelled dispersion demonstrated significantly improved stability after the gelation step.

Development of Stable Coenzyme Q10-Loaded Microemulsions Based on Dicaprylyl Ether

Pakpayat, Natthida, et al. Advanced Materials Research 1060 (2015): 70-73.

This study summarized the formulation and evaluation of environmentally friendly microemulsions (MEs) designed to encapsulate Coenzyme Q10 (CoQ10). Decylglucoside (biodegradable, non-ionic surfactant) and dicaprylyl ether as oil phase were used to develop stable and biocompatible carrier systems.
Formulation and Preparation
Two blank microemulsions, M1 and M2, were prepared using the following composition:
· M1: 70% dicaprylyl ether, 2.5% decylglucoside, 22.5% sorbatan monolaurate, and 5% water.
· M2: 60% dicaprylyl ether, 6% decylglucoside, 24% sorbatan monolaurate, and 10% water.
Each blank ME was subsequently loaded with 5% CoQ10, resulting in formulations labeled QM1 and QM2, respectively. All systems were prepared via simple mixing without complex processing.
Key Results:
· Both blank and CoQ10-loaded microemulsions exhibited transparency with no liquid crystal formation. The pH values ranged between 6.07 and 6.63. Rheological analysis revealed low viscosity and Newtonian flow behavior across all formulations.
· The formulations underwent stability testing through five freeze-thaw cycles. No significant changes in physicochemical properties were observed compared to initial values. Furthermore, CoQ10 recovery exceeded 97% in both QM1 and QM2 after stability testing.

• Synonyms: Dioctyl ether
• Molecular Weight: 242.44
• Molecular Formula: C16H34O
• Appearance: Liquid
• Application: Use as lubricant.; Use as dispersing agent.
• Active Content: 95%