Polylysine

Catalog Number

HG25104181

CAS

25104-18-1

Structure

Synonyms

L-Lysine, homopolymer;Poly(imino-(6-amino-1-oxo-2,1-hexanediyl), alpha-hydro-omega-hydroxy-

Appearance

Solid

Application

Use as dispersing agent, emulsifying agent.; Use as antistatic agent.; Use as water absorbing agent.

Active Content

95%

Case Study

Polylysine (PLL) Coating Imparts Durable Hydrophilicity and Antibacterial Function to Polyamide Fabric

Zhang, Wen, et al. Progress in Organic Coatings 142 (2020): 105571.

Challenge: One of the drawbacks of polyamide (PA) textile material is its poor comfort, which could be improved through hydrophilicity (enhanced wettability). Another drawback is its poor antibacterial function. Existing methods to graft functional biomolecules like ε-Polylysine (PLL) onto textiles are complex and costly.
Solution: Introduce a facile dip-coating technique for the surface functionalization of ε-Polylysine (PLL) onto PA fabric. Glutaraldehyde crosslinking via the Schiff base reaction between the amino groups of both PLL and PA provided strong binding to replace the previous tedious and expensive enzymatic/chemical grafting method.
Key Results:
· Dual Functionality: PLL inherently provides both antibacterial activity and hydrophilicity.
· Dramatically Improved Hydrophilicity: Confirmed by reduced wetting time, lower contact angle, increased moisture adsorption, and enhanced wicking.
· Effective Antibacterial Function: Imparted strong antibacterial properties.
· Excellent Washing Durability: Covalent bonding ensured lasting performance.
Conclusion: ε-Polylysine (PLL) is suitable for PA functionalization, with the help of dip-coating process. Natural biomolecule treatment to PA can change PA into comfortable and hygienic material with long-lasting hydrophilic and antibacterial function.

Polylysine (PLL) Enables Tunable, Salt-Responsive Stabilization in Soybean Oil Emulsions

Mundo, Jorge L. Muriel, et al. Food Research International 137 (2020): 109304.

Challenge: Oil-in-water emulsions are vital delivery systems but prone to breakdown under pH, salt, or temperature stresses. Achieving tailored stability across diverse conditions (e.g., food processing vs. human digestion) is difficult.
Solution: Researchers utilized cationic Poly-L-lysine (PLL) with anionic poly-glutamic acid (PGA) for layer-by-layer (LbL) electrostatic deposition onto lipid droplets in soybean oil-in-water emulsions. Primary droplets were stabilized with quillaja saponin.
Key Results:
· PLL successfully formed cationic layers on lipid droplets. PLL enabled precise modulation of droplet surface charge (ζ-potential), crucial for targeted emulsion behavior.
· The primary emulsion showed the best tolerance to various environmental conditions, while the secondary emulsion (PLL coating) showed the worst, indicating that electrostatic deposition should only be used to obtain specific functions.
· Salt-Responsive Detachment: PLL detached from droplet surfaces at high salt concentrations due to electrostatic screening.
· Smart Functionality: This detachment offers a unique benefit - emulsions can be designed to switch functionality (e.g., cationic during storage, becoming anionic upon salt exposure in the body).
Conclusion: PLL proves vital for engineering "smart" emulsions. Its salt-triggered detachment offers a unique strategy to create stimuli-responsive systems with switchable functionality, ideal for applications like food or pharmaceuticals requiring environment-specific behavior.

• Catalog Number: HG25104181
• CAS: 25104-18-1
• Synonyms: L-Lysine, homopolymer;Poly(imino-(6-amino-1-oxo-2,1-hexanediyl), alpha-hydro-omega-hydroxy-
• Appearance: Solid
• Application: Use as dispersing agent, emulsifying agent.; Use as antistatic agent.; Use as water absorbing agent.
• Active Content: 95%