Cellulose acetate

Catalog Number

HG9004357

CAS

9004-35-7

Synonyms

Acetylcellulose

Appearance

Solid

Application

Use as film-forming agent.; Use as sustained-release agent.; Use as adhesive.; Use as lubricant.; Use as non-metallic materials. For example, used in manufacturing of photographic film, film, glasses, cigarette filter, fiber.

Active Content

95%

Case Study

Solution Casting Process Study and Optimization of Cellulose Acetate Films

Kramar, Ana, et al. Cellulose 30.4 (2023): 2037-2052.

Challenge: Conventional solution casting of cellulose acetate films yielded inconsistent optical properties and adhesion issues, limiting advanced applications. Predictable control of film morphology and functionality is needed without complex process flows.
Solution: This study optimized CA film production by manipulating two critical variables including casting surfaces [borosilicate glass (smooth), soda-lime glass (smooth), PTFE (micro-textured)] and humidity (35%, 55%, 75% RH in controlled chambers). Process: 8-12% w/v CA/acetone solutions cast at 22°C.
Key Findings:
· Casting Surface Impact: Films cast on PTFE surfaces adopted micro-textured patterns, resulting in translucent films. These exhibited a reversible opacity shift: turning transparent when wet and reverting to translucent upon drying. Films cast on smooth glass surfaces (borosilicate or soda-lime) remained transparent but required pretreatment with chlorotrimethylsilane to prevent adhesion during demolding.
· Humidity Influence: Higher humidity (75% RH) during casting produced films with smoother surfaces and increased crystallinity. Humidity levels (35-75% RH) showed no measurable effect on film wettability.
· Functional Application: The humidity-triggered opacity transition in PTFE-cast films enables their use as visual moisture sensors - particularly valuable for intelligent food packaging solutions.

Enhanced Drug Delivery with Electrospun Cellulose Acetate Fiber Mats

Tungprapa, Santi, et al. Polymer 48.17 (2007): 5030-5041.

Aim: Compare drug release from electrospun (e-spun) Cellulose Acetate (CA) fiber mats versus solvent-cast CA films with four model NSAIDs (Naproxen/NAP, Indomethacin/IND, Ibuprofen/IBU, Sulindac/SUL).
Methodology: E-spun CA fiber mats (CA: Mw≈30,000 Da, DS≈2.4) with 20 wt% drug were made from 16% w/v CA solutions in acetone/DMAc (2:1 v/v). Cast films served as controls. For analysis, morphology, drug distribution, swelling in acetate buffer (37°C), and drug release (total immersion, acetate buffer, 37°C) were compared.
Key Results:
· Morphology & Encapsulation: E-spun mats had smooth, defect-free fibers (avg. diameters: 263-297 nm) with no surface drug aggregates indicating good encapsulation.
· Swelling: E-spun mats showed extensive swelling (570-630% weight gain in buffer), far greater than the negligible swelling of cast films.
· Drug Release: Drug release from e-spun mats was significantly higher than release from cast films at every time point for all four drugs.
· Drug-Dependent Release: Maximum cumulative release followed the same order: NAP > IBU > IND > SUL for both formats.
Conclusions: E-spun CA fiber mats have improved drug delivery performance over cast films because of their nanostructure resulting in high encapsulation, large swelling, and increased drug release rates. The extent of release is dependent on the drug type.

• Catalog Number: HG9004357
• CAS: 9004-35-7
• Synonyms: Acetylcellulose
• Appearance: Solid
• Application: Use as film-forming agent.; Use as sustained-release agent.; Use as adhesive.; Use as lubricant.; Use as non-metallic materials. For example, used in manufacturing of photographic film, film, glasses, cigarette filter, fiber.
• Active Content: 95%